n–3 Fatty Acids in Patients with Multiple Cardiovascular Risk Factors

· 2013
DOI: 10.1056/nejmoa1205409

The authors claim that treatment with n−3 polyunsaturated fatty acid does not reduce the risk of heart attacks.

  • :rating-4: Double-blind, placebo-controlled clinical trial
  • :rating-4: Decent sample size: 1383 events; 11200 patients
  • :rating-4: Claimed power: 90%
  • :rating-4: Detailed results, confidence intervals are provided
  • :rating-4: I found the protocol here, but it’s in Italian.
  • :rating-2: I’ve not found the raw data

Discussed in Statistics Done Wrong (page 84).

Reference

“n–3 Fatty Acids in Patients with Multiple Cardiovascular Risk Factors” (2013) DOI: 10.1056/nejmoa1205409

@Article{d101056nejmoa1205409_2013,
  title = {n–3 Fatty Acids in Patients with Multiple Cardiovascular Risk Factors},
  volume = {368},
  issn = {1533-4406},
  url = {http://dx.doi.org/10.1056/NEJMoa1205409},
  doi = {10.1056/nejmoa1205409},
  number = {19},
  journal = {New England Journal of Medicine},
  publisher = {Massachusetts Medical Society},
  year = {2013},
  month = {may},
  pages = {1800–1808}
}