Stopping Randomized Trials Early for Benefit and Estimation of Treatment Effects Systematic Review and Meta-regression Analysis
Excerpts
Nontruncated RCTs with no evidence of benefit … would on average be associated with a 29% relative risk reduction in truncated RCTs addressing the same question.
— Page 1184
Reference
Dirk Bassler “Stopping Randomized Trials Early for Benefit and Estimation of Treatment Effects Systematic Review and Meta-regression Analysis” (2010) DOI: 10.1001/jama.2010.310
@Article{bassler2010,
title = {Stopping Randomized Trials Early for Benefit and Estimation of Treatment Effects Systematic Review and Meta-regression Analysis},
volume = {303},
issn = {0098-7484},
url = {http://dx.doi.org/10.1001/jama.2010.310},
doi = {10.1001/jama.2010.310},
number = {12},
journal = {JAMA},
publisher = {American Medical Association (AMA)},
author = {Bassler, Dirk},
year = {2010},
month = {mar},
pages = {1180}
}